“Two turning points of rapid aging in the body… at 44 and 60 years old”

Changes in cardiovascular disease or caffeine/alcohol metabolism in mid-40s, immune regulation/carbohydrate metabolism/renal function changes in early 60s,
,
,

Aging
[Provided by Getty Images],
,
, ‘(Paris= Yonhap News) Correspondent Song Jin-won = An English daily, The Guardian, reported on the 14th local time that a study revealed that the human body ages rapidly at the ages of 44 and 60.’,
,
, ‘ Researchers at Stanford University in the United States analyzed the progress of aging by regularly collecting samples from 108 volunteers aged 25 to 75 for 1-7 years including blood, feces, swabs from skin, mouth, and nose.’,
,
, ‘ The researchers tracked 135,000 different molecules (RNA, proteins, metabolic products) and microbes (bacteria, viruses, fungi inhabiting the volunteers’ intestines and skin).’,
,
, ‘ Most molecules and microbes showed gradual or chronological changes.’,
,
, ‘ The researchers found a significant change in molecules and microbes around the mid-40s and early 60s.’,
,
, ‘ Regarding the bodily changes in the mid-40s, the researchers initially suspected that the overall group results were distorted due to changes before and after menopause in women.’,
,
, ‘ However, similar changes were found in men in their mid-40s.’,
,
, ‘ The molecules showing rapid changes in the mid-40s were mainly related to cardiovascular diseases or metabolism of caffeine, alcohol, and lipids.’,
,
, ‘ In the early 60s, changes were observed in molecules related to immune regulation, carbohydrate metabolism, and renal function.’,
,
, ‘ Molecules related to skin and muscle aging showed changes at both time periods.’,
,
, ‘ Previous studies indicated a rapid aging process around the age of 78, but since the oldest participant in this study was 75, the researchers explained that they could not confirm the results of the previous study.’,
,
, ‘ Senior author of this study, Professor Michael Snyder, a geneticist at Stanford University, explained, “We do not gradually change over time but experience a few dramatic changes” and described the mid-40s as a period of dramatic change like the early 60s.’,
,
, ‘ The researchers suggest that some of these molecular changes may be related to lifestyle habits or behavioral factors. For example, changes in alcohol metabolism function may occur in the mid-40s due to increased alcohol consumption during stressful times.’,
,
, ‘ Professor Snyder recommended, “If this study also shows when to increase physical activity, we still need to change our lifestyle habits while we are healthy.”‘,
,
, ” The results of this study were published in the international journal ‘Nature Aging’.”,
,
, ‘ [email protected]’,
,
,